Abstract：On the basis of the influence of the change of production factors' internal configuration on regional industrial enterprises' marginal output elasticity, this paper establishes Cobb-Douglas production function including production factors' internal configuration, and aims at analyzing regional industrial enterprises' innovation efficiency.It can be concluded as follows:the increasing percentage of regional foreign capital industrial enterprises can enhance marginal output elasticity of capital rapidly;the developing proportion of regional Hong Kong, Macao, Taiwan capital industrial enterprises can effectively improve marginal output elasticity of labor;the variables of workers' capacity, government subsidies, infrastructure and technology have different effects on industrial enterprises' innovative efficiency;the regional industrial enterprises lagging behind play a significant role of technological advantage of backwardness and keep up with the advanced ones
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