Abstract:China is in the period of economic transformation,local development needs to implement differentiated industrial and regional innovation policies,innovation model selection is a key link,fully confirm the importance and impact of innovation model selection is very necessary.Based on the characteristics of development frontier and heterogeneity,the manufacturing classification data of industrial enterprises above Jiangsu province in 2003—2018 were selected as typical provincial samples.This paper deeply reveals the internal mechanism of innovation mode selection in the innovation performance of industry under the action of endowment structure,and carries out heterogeneity analysis on the above action process.The results show the followings.In the process of industrial endowment structure influencing industrial innovation performance,the choice of innovation mode plays a part of intermediary role,and the regulation of innovation mode is the key factor that endowment structure positively affects industrial innovation performance.With the development of industrial innovation,the positive regulation of progressive innovation gradually weakens and changes to negative regulation,while the positive regulation of radical innovation has good stability.At the same time,the heterogeneity between industries weakens the positive regulation of radical innovation and enhances the positive regulation of progressive innovation.There is regional and industrial technology heterogeneity in the process of the effect of endowment structure and innovation mode choice on industrial innovation performance.